Model No. : 209216-23-9
Unit Price : 45
Entecavir hydrate ( CAS NO. 209216-23-9) is a nucleoside analog(more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Thera. Category: Adult chronic hepatitis...
Model No. : 19916-73-5
O6-Benzylguanine CAS 19916-73-5, also called 2-Amino-6-Benzyloxypurine is an essential intermediate for synthesis Entecavir. O6-Benzylguanine CAS NO 19916-73-5 is white solid which purity by HPLC is more than 99.2% and loss on drying is below 0.6%....
Model No. : 142217-81-0
Entecavir Intermediate CAS 142217-81-0, also known as Entecavir N8 and Entecavir-8 is white to off-white powder, which has the molecular formula of C26H27N5O3 and formula weight of 457.52. The purity of Entecavir Intermediate CAS NO 142217-81-0 by...
Model No. : 142217-77-4
Entecavir Intermediate CAS 142217-77-4, also known as Entecavir N4 and Entecavir-4 is white to off-white powder with the molecular formula of C32H33N5O4 and formula weight of 551.64. The reference standard purity of Entecavir Intermediate CAS NO...
Model No. : 110567-22-1
Entecavir Intermediate CAS 110567-22-1, also called Entecavir N3 and Entecavir-3 is offered with high purity and competitive price by our company. Entecavir Intermediate CAS 110567-22-1 appearance yellowish to light brown semi-fluid or liquid, which...
Model No. : 142217-78-5
Entecavir Intermediate CAS 142217-78-5, also called Entecavir N5 and Entecavir-5 is off-white to yellow solid with high purity and competitive price. The purity by HPLC is more than 98.5%, and the retention time of the major peak of the test...
Model No. : 202138-50-9
Tenofovir disoproxil fumarate CAS 202138-50-9 is the prodrug of tenofovir (PMPA, 2) ,which is new nucleotide reverse transcriptase inhibitors and mainly used for HIV clinically. We have deep analysis on the production situation of that hemifumarate...
Model No. : 202138-50-9
Tenofovir Disoproxil Fumarate CAS 202138-50-9 is one of the products with large-large scale production in our company whose intermediates monthly production capacity can be more than 50 tons. We have available inventory of tenofovir disoproxil...
Model No. : 202138-50-9
Our Tenofovir disoproxil fumarate (CAS 202138-50-9) API is manufactured according to in house standards. Thera. Category: Anti-hepatitis Cas No.: 202138-50-9 Synonym: Tenofovir disoproxil fumarate;TENOFOVIR...
Model No. : 209216-23-9
Unit Price : 45
Entecavir hydrate ( CAS NO. 209216-23-9) is a nucleoside analog(more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Thera. Category: Adult chronic hepatitis...
Some oncogenic RNA virus under the action of an enzyme produced by itself, is able of RNA as a template,according the RNA nucleotide sequence to the synthesis of DNA, this enzyme is called Reverse Transcriptase. Reverse Transcriptase can inhibit activity of this enzyme , Transcriptase Inhibitors can be divided nucleoside Reverse Transcriptase Inhibitors NRTLs and non-nucleoside Reverse Transcriptase Inhibitors NNRTLs according the main chemical structure currently.
Nucleoside reverse transcriptase inhibitors is develop more varieties of a class of drugs, clinically are proven to have a strong inhibitory effect on HIV replication, nucleoside reverse transcriptase inhibitors (NRTIs), it is a synthetic DNA of HIV reverse transcriptase substrate deoxynucleotide analogues, an active derivative of the nucleoside triphosphates in vivo, and combined deoxynucleoside triphosphates of natural competition with HIV reverse transcriptase (RT) , inhibit RT, hinder former synthetic virus. By blocking the formation of double-stranded DNA virus, and let the virus lose replication template. First, these drugs enter into the infected cells, and the formation of active phosphorylated dideoxynucleoside triphosphate compounds, competitive inhibition of HIV reverse transcriptase which could cause premature termination of the synthesis of a DNA strand, whereby virus replication was inhibited. Early treatment for AIDS and its related syndromes, it has certain effect for the treatment of HIV-positive / AIDS, can reduce mortality and opportunistic infections, but they can not cure AIDS. NNRTIs (non-nucleoside reverse transcriptase inhibitors): reverse transcriptase inhibitors and nucleoside reverse transcriptase to act on the substrate binding site of different mechanisms. At this stage there are five inhibitors which are approved by FDA nevirapine, delavirdine, efavirenz, etravirine and Rilpivirine. Wherein nevirapine, delavirdine belong to the first generation of NNRTIS, efavirenz for the second generation inhibitors, these two types of inhibitors have been used for more than a decade and produces a stable resistant strains. etravirine and Rilpivirine is the third-generation non-nucleoside reverse transcriptase inhibitors, currently it plays an important role in the clinical treatment.
Conbottpharm could give you:
1. Best quality in your requirement