Payment Type: | T/T,L/C |
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Model No.: 202138-50-9
Brand: CONBOTTPHARM
Packaging: 25KGS/DRUM
Productivity: Customized
Transportation: Air
Place of Origin: CHINA
Supply Ability: Commercial
Certificate: DOCUMENT SUPPORT
Payment Type: T/T,L/C
Tenofovir disoproxil fumarate CAS 202138-50-9 is the prodrug of tenofovir (PMPA, 2) ,which is new nucleotide reverse transcriptase Inhibitors and mainly used for HIV clinically. We have deep analysis on the production situation of that hemifumarate and impurities relevant to this drug. We have a relevantly complete iimpurity file system,stable production environment and adequate inventory.
Tenofovir disoproxil fumarate CAS 202138-50-9 listed for the treatment of AIDS in 2001 which was also approved for the treatment of chronic hepatitis B in 2008. It`s featured for its good tolerance, low resistance, withdrawal rebound rate, renal toxicity and so on. Especially it has a relatively good clinic application prospect for patients with HIV and HBV infection. It has water solubility, and can be rapidly absorbed and degraded into tenofovir which is adenosine monophosphate acyclic nucleoside analogues which will phosphorylated to tenofovir bisphosphonates under the function of cell kinases It inhibits the virus in the following two ways: one is to competitively combine with natural deoxyribose substrates to inhibit viral polymerase; the other way is to insert into virus DNA and cause DNA chain elongation termination, thus play achieving the effect of curing AIDS and hepatitis B.
Product Categories : Inhibitors > Reverse Transcriptase Inhibitor