Company Details
  • Conbott Pharmtech Co.,Ltd.

  •  [Zhejiang,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:71% - 80%
  • Certs:COS, ISO9001, ISO14010, FDA
  • Description:Jak Inhibitors,Jak Kinase Inhibitor,Substrate Jak Inhibition
Conbott Pharmtech Co.,Ltd. Jak Inhibitors,Jak Kinase Inhibitor,Substrate Jak Inhibition
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JAK Inhibitors

Product categories of JAK Inhibitors, we are specialized manufacturers from China, Jak Inhibitors, Jak Kinase Inhibitor suppliers/factory, wholesale high-quality products of Substrate Jak Inhibition R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
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Ruxolitinib (INCB018424) JAK Inhibitor CAS 941678-49-5 
Ruxolitinib (INCB018424) JAK Inhibitor CAS 941678-49-5 

Model No. : 941678-49-5 

Ruxolitinib with CAS number of 941678-49-5 and 1092939-17-7 is short for (R)-3-(4-(7H-Pyrrolo [2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile. It is a off-white solid with purity of ≥99% by HPLC. Molecular Formula is C17H18N6 and...

China Manufacturer of Jak Inhibitors
Peficitinb Intermediates for Synthesis JAK Inhibitor CAS 920966-13-8
Peficitinb Intermediates for Synthesis JAK Inhibitor CAS 920966-13-8

Model No. : 920966-13-8

In order to fulfill the ever changing demands of our clients, we are engaged in offering high quality Peficitinb Intermediates CAS 920966-13-8. Peficitinb is a useful orally bioavailable JAK inhibitor. The Peficitinb Intermediates CAS NO...

High Quality Jak Kinase Inhibitor China Supplier
Peficitinb (ASP015K, JNJ-54781532) Intermediates CAS 920966-13-8
Peficitinb (ASP015K, JNJ-54781532) Intermediates CAS 920966-13-8

Model No. : 920966-13-8

We are professional 1H-Pyrrolo[2,3-b]Pyridine-5-CarboxaMide, 4-Chloro- CAS 920966-13-8 manufacture, supplier and exports. It is a kind of useful intermediate of Peficitinb. We can offer a range of high purity Peficitinb Intermediates CAS NO...

Professional Manufacturer of Substrate Jak Inhibition
Intermediate of Filgotinib Synthesis JAK1 Inhibitor CAS 59801-62-6
Intermediate of Filgotinib Synthesis JAK1 Inhibitor CAS 59801-62-6

Model No. : 59801-62-6

Thiomorpholine 1,1-dioxide Hydrochloride CAS 59801-62-6 is an important product in our company. It widely used to synthesis Filgotinib. Filgotinib Intermediates CAS NO 59801-62-6 is micronized white powder with the molecular formulaC4H10ClNO2S and...

Expert Manufacturer of Jak Inhibitors
Thiomorpholine 1,1-dioxide HCl CAS 59801-62-6
Thiomorpholine 1,1-dioxide HCl CAS 59801-62-6

Model No. : 59801-62-6

Thiomorpholine 1,1-dioxide Hydrochloride CAS 59801-62-6, also called Thiomorpholine 1,1-dioxide HCl. It is an important intermediate for Filgotinib. Filgotinib(also named GLPG0634) is a selective JAK1 inhibitor which shows higher selectivity. Being...

China Supplier of Jak Kinase Inhibitor
Highly Effective Filgotinib(GLPG0634) Intermediate CAS 1142943-96-1
Highly Effective Filgotinib(GLPG0634) Intermediate CAS 1142943-96-1

Model No. : 1142943-96-1

Filgotinib Intermediate CAS 1142943-96-1 is one of the most important products in our company. Processed Filgotinib Intermediate CAS NO 1142943-96-1 adopt precise formulation ingredients and cutting edge technology. Filgotinib Intermediate...

China Factory of Substrate Jak Inhibition
Filgotinib Intermediate Synthesis JAK1 Inhibitor CAS 1142943-96-1
Filgotinib Intermediate Synthesis JAK1 Inhibitor CAS 1142943-96-1

Model No. : 1142943-96-1

Cyclopropanecarboxylic Acid (5-Bromo-[1,2,4]Triazolo[1,5-a]Pyridin-2-yl)-Amide is another primary intermediates for Filgotinib (GLPG0634). We can offer a range of high quality Filgotinib Intermediates CAS 1142943-96-1 and related production. Our...

Jak Inhibitors Export
Bulk Production Filgotinib (GLPG0634) CAS 1206161-97-8
Bulk Production Filgotinib (GLPG0634) CAS 1206161-97-8

Model No. : 1206161-97-8

We are offering a range of high purity Filgotinib(GLPG0634) CAS 1206161-97-8 to our customers. Filgotinib (GLPG0634) CAS NO 1206161-97-8 is known as a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and...

Competitive Jak Kinase Inhibitor China Supplier
Selective JAK1 Inhibitor Filgotinib (GLPG0634) CAS 1206161-97-8
Selective JAK1 Inhibitor Filgotinib (GLPG0634) CAS 1206161-97-8

Model No. : 1206161-97-8

We are well known in the market for offering Filgotinib CAS 1206161-97-8, also known as GLPG0634. Filgotinib (GLPG0634) CAS NO 1206161-97-8 is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2,...

Leading Manufacturer of Substrate Jak Inhibition
JAK3 Inhibitor Decernotinib Intermediates CAS 916176-50-6
JAK3 Inhibitor Decernotinib Intermediates CAS 916176-50-6

Model No. : 916176-50-6

As we all known, Decernotinib (VX-509) is a potent and selective JAK3 inhibitor with Ki of 2.5 nM, >4-fold selectivity over JAK1, JAK2, and TYK2, respectively. We are specialized in offering customers with a remarkable assortment Decernotinib...

Professional Factory of Jak Inhibitors
C20H23BN2O4S, Decernotinib(VX-509) Intermediates CAS 916176-50-6
C20H23BN2O4S, Decernotinib(VX-509) Intermediates CAS 916176-50-6

Model No. : 916176-50-6

Decernotinib(VX-509) Intermediates CAS 916176-50-6 the chemical named is 1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine-4-Boronic Acid Pinacol Ester which is white powder. The Decernotinib(VX-509) Intermediates CAS NO 916176-50-6 is micronized and on sterile...

High Quality  Tofacitinib CAS 477600-75-2
High Quality Tofacitinib CAS 477600-75-2

Model No. : 477600-75-2

We processed Tofacitinib CAS 477600-75-2 is strictly according to industry standard. The specification is micronized and on sterile level. Tofacitinib CAS NO 477600-75-2 is widely used to treatment of rheumatoid arthritis (RA). Apart from this, It...

China JAK Inhibitors Suppliers

JAK Inhibitors are newly discovered targets in recent years, mainly for the screening of blood diseases, cancer, rheumatoid arthritis and psoriasis treatment.
Janus kinase and signal transducer and activator of transcription (Janus-activatedk-ina-sSignaltransducersandactivatorsoftranscription, JAK / STAT) is closely related to a newly discovered cytokine recently which is a intracellular signal transduction pathways, It plays many important biological processes involved death,immune regulation,proliferation and differentiation. Janus kinase is a non-receptor tyrosine kinase. There are four members in the family JAK1, JAK2, TYK2 and JAK3. The first three are widely existed in various tissues and cells, while JAK3 is only existed in the bone marrow and lymphatic system. Janus kinase is a very important drug target, Jak Inhibitors is based on this targets and design.
Rheumatoid arthritis is a common clinical chronic autoimmune disease, the pathogenesis of synovial tissue and large number of cells secrete cytokines were activated by JAK / STAT signaling pathway through different pathways and lead to disease. Therefore, choice the JAK inhibitor, targeted to block JAK / STAT pathway, it will help to improve the pathological process of rheumatoid arthritis purpose.
Numerous clinical studies summarized that JAK Inhibitors were used to treat idiopathic myelofibrosis, rheumatoid arthritis, psoriasis and other diseases, all are showed good efficacy, safety and tolerability, especially Ruxolitinib was already submitted as a New Drug application to the FDA in July 2011, it is expected to become the first listed JAK inhibitors.
Due to JAK inhibitor has good development prospects,it attracted many large companies investing in the development, investmentvalues is more than 50 billion US dollars. Thus, JAK inhibitor owns prospects market, worthy to be attention.

Conbottpharm could give you:
1. Best quality in your requirement
2. Competitive price in China market
3. Mature Technical support
4. Professional logistic support
All we want is win-win business. Send yr. inquiries, you will get it!
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