Company Details
  • Conbott Pharmtech Co.,Ltd.

  •  [Zhejiang,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:71% - 80%
  • Certs:COS, ISO9001, ISO14010, FDA
  • Description:Bcl-2 Inhibitor,Selective Bcl-2 Inhibitor,Bcl-2 Receptor Inhibitor
Conbott Pharmtech Co.,Ltd. Bcl-2 Inhibitor,Selective Bcl-2 Inhibitor,Bcl-2 Receptor Inhibitor
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BCL-2 Inhibitor

Product categories of BCL-2 Inhibitor, we are specialized manufacturers from China, Bcl-2 Inhibitor, Selective Bcl-2 Inhibitor suppliers/factory, wholesale high-quality products of Bcl-2 Receptor Inhibitor R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
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R&D BCL-2 Inhibitor Venetoclax Intermediates CAS 1228780-72-0
R&D BCL-2 Inhibitor Venetoclax Intermediates CAS 1228780-72-0

Model No. : 1228780-72-0

We are one of the leading manufacturer, supplier and exporter of Venetoclax (ABT-199, GDC-0199) Intermediates CAS 1228780-72-0. The intermediates of Venetoclax is small molecular and micronized that ensure the Venetoclax Intermediates CAS NO...

China Manufacturer of Bcl-2 Inhibitor
Potent Venetoclax (ABT-199, GDC-0199) Intermediates CAS 1228780-72-0
Potent Venetoclax (ABT-199, GDC-0199) Intermediates CAS 1228780-72-0

Model No. : 1228780-72-0

Over the years of experience in the industry, we are engaged in offering a range of precise formulation Venetoclax Intermediates CAS 1228780-72-0 to our customers. Venetoclax is a small molecule oral drug being investigated to treat chronic...

High Quality Selective Bcl-2 Inhibitor China Supplier
Selective BCL-2 Inhibitor Venetoclax Intermediates CAS 1228779-96-1
Selective BCL-2 Inhibitor Venetoclax Intermediates CAS 1228779-96-1

Model No. : 1228779-96-1

With the aid our competent team of professionals, we are engaged in offering high purity Venetoclax intermediates CAS 1228779-96-1 to our customers. As we all known, Venetoclax is a potent Bcl-2-selective inhibitor to treatment of chronic...

Professional Manufacturer of Bcl-2 Receptor Inhibitor
MFCD28142285, ABT-199 Intermediates CAS 1228779-96-1
MFCD28142285, ABT-199 Intermediates CAS 1228779-96-1

Model No. : 1228779-96-1

Backed by a team of dexterous professionals, we have been able to offer best quality Venetoclax (ABT-199) intermediates CAS 1228779-96-1 to our customers. Available in a packaging of 25kg drum Venetoclax (ABT-199) intermediates CAS NO 1228779-96-1...

Expert Manufacturer of Bcl-2 Inhibitor

China BCL-2 Inhibitor Suppliers

Bcl-2 family of proteins first discovered in B-cell lymphomain of chromosomal translocations have No. 14, 18, it is a lymphoma translocation gene protein. This typical chromosomal translocations can occur in 70-95% of follicular lymphoma. One of the most important features of cancer that does not follow the normal cell death program (apoptosis) and excessive proliferation. In the process of apoptosis, Bcl-2 family proteins play an important role. Bcl-2 family of proteins is important on the regulation of outer mitochondrial membrane (OMM) integrity, in the intrinsic pathway of apoptosis, and determines the sensitivity of cells to apoptotic response. Meanwhile, in-depth study of Bcl-2 family members, provide targets for the development of new anticancer drugs.
The past, many natural products are considered to be potential Bcl-2 Inhibitors, such as antimycin A (AMA). It is reported that in human kidney cancer treatment, AMA is able to enhance the expression of DR5, inhibited the expression of Bcl-2, and enhance tumor necrosis factor-related apoptosis-inducing ligand induced apoptosis. Celandine base is a plant alkaloid, which can disrupt the formation of Bcl-xl / Bax complex, thereby inhibiting tumor growth, through the activation of the mitochondrial pathway, celandine base regulate Bcl-2 protein family expression to induce apoptosis. Studies have shown that a dose of CHE (chelerythrine chloride, celandine base chloride) can damage the mitochondrial membrane potential, release of cytochrome C, activation of caspase-3 and poly ADP-ribose polymerase cleavage to induce apoptosis .
Bcl-2 inhibitors will undoubtedly become a hot research field of anticancer drugs, the application of computer-aided techniques to design, screening or optimized to Bcl-2 as a target for small-molecule inhibitors compared to conventional methods exhibit certain advantages. On the basis of further research on tumor cell apoptosis mechanism, breaking the resistance to future research is still anti-tumor drug development difficult.


Conbottpharm could give you:
1. Best quality in your requirement
2. Competitive price in China market
3. Mature Technical support
4. Professional logistic support
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